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doi: 10.3389/fimmu.2022.1098725 237 NiuYChenXXiaoLLiWFengLAierkenA

Advances in the research of mechanism and related immunotherapy on the cytokine storm induced by coronavirus disease 2019

A cystine-glutamate antiporter then exchanges this cystine for glutamate, activating inhibitory metabotropic glutamate receptors named Group II metabotropic glutamate receptors (mGlu2/3 receptors) on glutamatergic nerve terminals and lowering synaptic glutamate release