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Glutathione is a naturally occurring Antioxidant found in our body, primarily in the liver

doi: 10.1016/j.neubiorev.2010.10.002 86

Ashlyn Ryan Crawford, Gilbertsville, PA

In contrast, persistently stabilized NRF2 in response to KEAP1 or NRF2 mutations causes sustained activation of these genes, leading to the accumulation of xCT/SLC7A11, GCLC, and GCLM that cause a depletion of intracellular glutamate (Sayin et al

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