mk571 mrp1 glutathione efflux Protection against Oxidative Stress in Beta Thalassemia/Hemoglobin E Erythrocytes by Inhibitors of Transporters Nitrogen monoxide (NO)-mediated iron release

Nitrogen monoxide (NO) mediated iron release from cells is linked to NO induced glutathione efflux via multidrug resistance associated protein 1 PNAS In vitro function and in situ localization of Multidrug Resistance associated Protein (MRP)1 (ABCC1) suggest a protective role against methyl mercury induced oxidative stress in the human placenta Archives of Toxicology Springer Inhibition of the MRP1 mediated transport of the menadione glutathione conjugate (thiodione) in HeLa cells as studied by SECM PNAS Genomic discovery and functional validation of MRP1 as a novel fetal hemoglobin modulator and potential therapeutic target in sickle cell disease medRxiv In differentiated HL 60 neutrophil like cells, MRP1 (ABCC1 ) mediated glutathione efflux stimulated by BzATP and P2X7 receptor signalling regulates exosome release through nSMase activity bioRxiv

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