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Nevertheless, in animals subjected to CSD and received ALA administration, the levels of all above signaling proteins were noticeably reduced to near the control values (Figure 5A)

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Recent studies have found that inhibition of the phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)/NF-B signaling pathway mediated by lipopolysaccharide (LPS) and TMAO can significantly suppress inflammation, cell apoptosis, and oxidative stress in AKI [86]

At present, several types of medicinal coral resources are identified, which are used in 56 formulas such as traditional Chinese medicine, Tibetan medicine, Mongolian medicine, and Uyghur medicine