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Damage to mitochondrial DNA results in loss of mitochondrial membrane potential, impairment in the electron transport chain, and drives the immune and inflammatory responses (Liu and Chen, 2017), (Figure 3)

Although MIF shares low sequence homology with natural ligands, such as CXC motif chemokine ligand (CXCL8) and SDF-1 (CXCL12), it contains specific motifs that enable receptor binding upon protein folding

Routes of exposure: Following release of sarin into the air, people can be exposed through skin contact or eye contact

Neuroscience 289:36780 Fiorini AC, Scorza CA, de Almeida AC, Fonseca M, Finsterer J, Fonseca FL, Scorza FA (2021) Antiviral activity of Brazilian green propolis extract against sars-cov-2 (Severe acute respiratory syndrome-coronavirus 2) infection: case report and review

Metrnl alleviates lipid accumulation by modulating mitochondrial homeostasis in diabetic nephropathy