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Exogenous pathways rely on the inhibition of system Xc (cystine/glutamate transporter) and the activation of the transferrin and transferrin receptor 1, while the endogenous pathway mainly involves blocking the activation of GPX4 (Xue et al., 2023)

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Vitamin B12 is key for our health, helping make myelin and neurotransmitters

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As an attractive target for regulating macrophage metabolism, unlike RONS, which have been extensively studied, researchers need to explore NM-modulated succinate oxidation to address this gap in our understanding of defense against diseases

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Personalized metabolic analysis is indispensable for crafting tailored treatment protocols, ultimately providing more accurate medical solutions for patients

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