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The -carotene activity towards peroxyl radicals and the stability of other carbon-centred radicals are the two main features that provide the carotene molecule with its antioxidant properties (Fiedor and Burda, 2014)

When Nrf2 is degraded by E3 ubiquitin ligase (MIB1), the antioxidant capacity of lung cancer cells is weakened, and the sensitivity of lung cancer cells to ferroptosis inducers is enhanced [91]

798,799 Intravenous injection of histochrome significantly reduces cardiac fibrosis, increases capillary density, and significantly improves cardiac function in I/R rats by upregulating the expression of Nrf2 and its downstream genes, including GPX4, and reducing intracellular and mitochondrial ROS levels

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Typically, such compositions are prepared either as liquid solutions or suspensions, however solid forms such as tablets, pills, powders and the like are also contemplated