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No significant differences in oral bioavailability were identified between subjects with T2D and healthy subjects, which was in accordance with the results from the trial reported by Granhall and colleagues [27], which demonstrated similar semaglutide exposure in male subjects with and without T2D

FASEB J (2022) 36(1):e22078

Key Takeaways Peptide bioavailability depends heavily on the delivery method, with absorption, stability, and systemic exposure varying by route of administration

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It should not be considered a substitute for PRP, stem cell therapies, or advanced image-guided musculoskeletal treatments