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Figures 1B , 3 ) is not fully ameliorated by conventional subcutaneous insulin administration, most likely because subcutaneous administration of insulin cannot fully compensate for the normal portal delivery of insulin to the liver

Age can also play a role, as stomach acid production often decreases in older individuals

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10.1016/j.surg.2004.03.012 63 MatsumotoK.MiyakeY.UmedaY.MatsushitaH.MatsudaH.TakakiA.et al (2013)

These models highlight distinct pathological and temporal features of AD, including early synaptic changes and amyloid accumulation, providing valuable tools for studying disease progression and potential therapeutic targets