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Description

Chen VB, Arendall WB 3rd, Headd JJ, Keedy DA, Immormino RM, Kapral GJ, Murray LW, Richardson JS, Richardson DC

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Hydrophilic molecules traverse the lipid bilayer via selective transport systems, while large molecules and polar drugs require overcoming the tight junction structure and utilizing the paracellular transport pathway for absorption

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Nat Chem Biol 13(1):6974

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