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ROS production and associated inflammation are closely related to aging and numerous chronic diseases as diabetes, cardiovascular atherosclerosis-related diseases (144, 145) and respiratory diseases, known risk factors for developing severe illness and death in patients with SARS-CoV-2 and COVID-19 disease

doi: 10.3389/fncel.2016.00296 Received 11 August 2016 Accepted 13 December 2016 Published 04 January 2017 Volume 10 - 2016 Edited by Hansen Wang, University of Toronto, Canada Reviewed by Adelaide Fernandes, Universidade de Lisboa, Portugal

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