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These findings were challenged by a more recent in vitro study, using fecal microbiota from healthy donors (Peng et al., 2024)

Ikeno H, Tochio T, Tanaka H, Nakata S

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10.1186/s12916-020-01697-5 BMC Med

Empirical Rule: Each 1000 IU of Vitamin D 3 daily raises serum 25(OH)D by approximately 710 ng/mL (more pronounced at lower baseline levels) (guideline and expert opinion) (67, 68)