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[Abstract]2019 Jul 24;9(1):35-48.e5

Rahmattulla et al

The nature of the cholinergic hypothesis is based on the suppressed synthesis of the neurotransmitter acetylcholine and therefore the therapeutic intervention is based on the restoration of the physiological level of acetylcholine by inhibiting the activity of enzyme acetylcholinesterase (AChE) (Bartus et al