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Compared with the IDD group, IDD mice injected with hADSCs showed increased disc height index, MRI index and mean T2 intensities, as well as the attenuated histologic grading of the annulus fibrosus (AF) and NP accompanied by the upregulation of GAG and COL2

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Additional tests may include methylmalonic acid, intrinsic factor antibodies, and investigation for malabsorption conditions following British Society for Haematology and NICE guidance

The cystine is added separately at final 0, 5 or 48.3 mg/L (equivalent to 0, 30, and 292 M), depending on experiments

If offering peptides outside approved indications, clinicians should present use as experimental, disclose regulatory status and paucity of clinical studies, describe known and unknown risks, and outline standard treatment alternative (e.g