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Positive results from the Phase II WILLOW study and Phase III ASPEN study demonstrate that compared to placebo controls, DPP1 inhibition treatment can significantly extend time intervals to first acute exacerbations in bronchiectasis patients and effectively reduce overall acute exacerbation occurrence frequency (Zhong et al., 2025

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Adjusting protocols based on progress requires thoughtful interpretation of available data

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13 These and other studies have established CD38-directed monoclonal antibodies in combination regimens as a standard of care across multiple lines of therapy for relapsed/refractory multiple myeloma