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Furthermore, IL-1 stimulates cerebral vascular endothelial cells to highly express adhesion molecules such as ICAM-1 and VCAM-1, leading to the substantial recruitment of inflammatory cells like neutrophils to the lesion site, which exacerbates inflammatory infiltration and secondary damage (103)

Recent studies have shown that levodopa and dopamine suppress glucose-dependent insulin secretion by reducing the frequency of intracellular calcium current oscillation [141]