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Reference lists of included articles and relevant reviews were manually screened to identify additional pertinent studies

Injections are usually administered subcutaneously (under the skin), once a month, in your vets office

Folate is a B vitamin that is essential for many bodily functions, including DNA synthesis and repair, red blood cell formation, and nerve function

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You draw a specific volume of bacteriostatic water into a syringe, inject it slowly into the vial, and gently mix until the powder dissolves completely