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The degeneration may be in the form of lesions in the central nervous system, as in multiple system atrophy (MSA), or in loss of autonomic nerves not involving the central nervous system, as in pure autonomic failure (PAF)

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This enhanced microcirculation results in increased nutrient delivery to injury sites and more efficient waste removal, accelerating overall healing timelines

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PMID: 40094857 Cell Rep Microglial macrophage-derived ds-HMGB1 in DRG orchestrates neuropathic pain through immune-neural signaling