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A boom online has seen unregulated lab-made peptides being touted as a cure-all or quick fix

Here we report cryo-electron microscopy (cryo-EM) structures of human OCTN2 in a substrate-free inward-facing conformation, a substrate-bound occluded conformation, and an ipratropium-bound inward-facing conformation, revealing how OCTN2 binds and transports carnitine

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Melatonin reduces endoplasmic reticulum stress and corneal dystrophy-associated TGFBIp through activation of endoplasmic reticulum-associated protein degradation