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Furthermore, the suppression or down-regulation of anti-infectious immunity mediated by the parasites or their derived molecules can compromise the effect of parasitic vaccines

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Peroxisome proliferator-activated receptor delta-agonist, GW501516, ameliorates insulin resistance, improves dyslipidaemia in monosodium L-glutamate metabolic syndrome mice We examined the effects of GW501516, a specific agonist for peroxisome proliferator-activated receptor beta/delta (PPARdelta), in mice with metabolic syndrome induced by perinatal monosodium L-glutamate injection

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Nat Rev Drug Discov 20:689709

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