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Studies on MOTS-c highlight its role in mitochondrial signaling, insulin sensitivity, and metabolic regulation

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Researchers exploring this route typically begin with conservative doses and titrate based on observed effects

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doi: 10.2174/156802606775270288

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While this is less than what GLP-1 medications achieve over longer treatment courses, phentermine offers distinct advantages: it's an oral medication (no injections), it's widely available as a generic, and it's covered by many insurance plans

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