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Theriogenology 157:218225

Fibroblast migration allows these cells to reach sites of inflammation and respond to this inflammation by depositing collagen and other ECM proteins

Pridgeon JW, Olzmann JA, Chin L-S, Li L

Instead of speeding up surface turnover, it signals fibroblasts in the deeper dermal layer to support collagen and elastin, and it carries copper for the enzymes that help cross-link new collagen

The decrease of autophagic vacuoles, together with the decrease of LC3B and increase of p62, suggested that the autophagic degradation process, also known as autophagy flux, was blocked in AA patients ( Figures 3 and 5 )