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In addition to cytoskeletal dynamics influencing FBP production via aldolase regulation, another trigger for increased glycolysis might be an elevated glucose uptake during cell migration 60

While MTHFR can impact folate processing, which is crucial during pregnancy, managing folate intake through diet and/or supplements can reduce the risk of complications

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Lymphatic targeting may be achieved via the delivery of macromolecular therapeutics (for example, proteins and peptides), small-molecule therapeutics in association with macromolecular carriers (for example, nanoparticles, polymers, liposomes and dendrimers) or small-molecule therapeutics that associate, in situ , with endogenous macromolecular constructs (for example, lipoproteins and proteins) or cells that are transported from interstitial tissues via lymphatic rather than blood capillaries