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Of course, additional studies of larger cohorts of ICI-treated patients with different cancers will be needed to validate these findings

doi: 10.3389/fbioe.2021.802031 Received 26 October 2021 Accepted 08 December 2021 Published 14 February 2022 Volume 9 - 2021 Edited by Fengjie Cui, Jiangsu University, China Reviewed by Xuetuan Wei, Huazhong Agricultural University, China Zaiwei Man, Changzhou University, China Updates Copyright 2022 Peter, Qiao, Godspower, Ajeje, Xu, Zhang, Yang and Rao

This marker was increased in mutSOD1 from C1, compared to the respective control (Fig.3 a), which is negatively correlated with the changes observed in SOD1 protein levels and total SOD activity in this cohort (Fig.2 c-d)

doi:10.3390/ijms222111904 99

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