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In a mouse PD model induced by -synuclein preformed fibrils (PFFs), EGCG treatment decreased TNF- and IL-6 expression, reduced pathological aggregation, increased survival of dopaminergic neurons in the substantia nigra, and improved both motor and anxiety-like behaviors (53)

Their concentration within the bodys cells tends to decline with age and metabolic demand

(55) further demonstrated that in models of PD and other neurodegenerative diseases, EGCG exerts neuroprotective effects via NF-B signaling inhibition by blocking IB phosphorylation and suppressing p65 nuclear translocation, thus downregulating pro-inflammatory cytokines such as TNF- and IL-1 and reducing dopaminergic neuronal loss and motor dysfunction

Oral supplements, intravenous treatments, and combined therapy protocols should always be guided by qualified medical professionals

It supports the production of ATP, the primary energy source for muscles, promoting vitality and stamina YOUTH & LONGEVITY: Nicotinamide D-Ribose uses Bioenergy Ribose and supports healthy blood flow and heart health by reducing oxidative stress and inflammation