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KYN levels were elevated (~ 2.1-fold), and TDO expression (both glial density and intensity in grey and white matter) was significantly higher, suggesting that enhanced KP metabolism may contribute to psychotic features in bipolar disorder

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Chiral inversion of 2-arylpropionyl-CoA esters by human -methylacyl-CoA racemase 1A (P504S)a potential mechanism for the anti-cancer effects of ibuprofen