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Reduced Fatigue and Increased Motivation : Many individuals on weight loss or fitness journeys struggle with fatigue, which can hinder progress

Several factors cause this: Lower stomach acid production [6] Less intrinsic factor [6] Interference from medications (especially proton pump inhibitors and metformin) [6] Atrophic gastritis affects 8-9% of adults over 65, which makes nutrient absorption even harder [7]

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doi:10.1201/9781315119540

Patients starting semaglutide are often already on metformin or proton pump inhibitors (which block tablet absorption)