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Yazici, H

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This effect has made it popular in skin-whitening treatments

Pan-cancer studies further validate IPAs causal role: its supplementation improves ICI response rates across malignancies (110, 159), while ATB-induced microbiota depletion reduces IPA levels and blunts T cell-mediated tumor controlan effect reversed by exogenous IPA, which directly upregulates granzyme B/perforin in T cells (111)

Rathi A, Bahugana Y, Nagar M (2023) An overview on cardio-protective compound dexrazoxane