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By contrast, in CD8 T cells, deficiency of these NF-B early signaling intermediates raises the threshold of TCR signaling required for proliferation, resulting in impaired CD8 T cell proliferation even with strong agonistic TCR stimulation (78)

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We demonstrated that the BPC 157 treatment protocol was also efficacious when it was applied on day 3, immediately after the constricting ring was removed (Table 3, Figures 18 and 20-22), as shown by its subsequent rapid effect on the appearance of the arcade vessels