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doi: 10.3389/fphar.2017.00622 467 KausarNShierWTAhmedMAlbekairiNAAlshammariASaleemMet al

illness, trauma) mean that supplementation is required

3: 717-727 Gustafsson A and Mannervik B: Benzoic acid derivatives induce recovery of catalytic activity in the partially inactive Met208Lys mutant of human glutathione transferase A1-1

They act as resident macrophages, responding to pathogenic invasion, tissue damage, and protein aggregates by recognising danger-associated molecular patterns (DAMPs) or pathogen-associated molecular patterns (PAMPs) through specific receptors [42,43,44]

However, we cannot exclude that treatment related malnutrition in some patients might have affected the metabolite blood plasma levels during and after treatment