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Description

The prepared Desmond model systems were then loaded onto Molecular Dynamics (MD) panel (Schrdinger 2023-2) to run a 1000-ns all-atom MD simulation with 1.0-ps recording interval

Domest Anim endocrinol

Formation of the K d-la modification was performed on a 25 mol scale by addition of d-lactic acid (11.3 mg, 0.125 mmol, 5.0 equiv.), HATU (46.7 mg, 0.123 mmol, 4.9 equiv.) and i Pr 2 NEt (35 l, 0.200 mmol, 8.0 equiv.) in DMF (1.25 ml) at room temperature (2 45 min), followed by washing with DMF (3 4 ml) and CH 2 Cl 2 (3 4 ml)