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Oxidation induces a Cl(-)-dependent cation conductance in human red blood cells

This is a well-documented pre-clinical window, and it is where functional medicine practitioners have the most leverage, if we know what to look for and when to look

It has been suggested that ferroptosis has a critical role in decreased viability of chondrocytes in OA, and here, we review recent findings regarding the pathologic pathways that lead to chondrocyte ferroptosis, and discuss the possible therapeutic utility of ferroptosis inhibition in OA