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It is important to stress that insufficient levels of B12 raise susceptibility to infections and diseases, and are very harmful to the nervous system which in turn can cause neurological disorders and severe and sometimes irreversible nerve damage

Mood and anxiety settle: Because B12 supports the nervous system, low mood tied to deficiency often eases once levels are restored

In particular, thiamine (B1) tends to be rapidly depleted during alcohol consumption

That includes mood shifts, low energy, hot flashes or night sweats, vaginal dryness, low libido, or painful sex

When used together, these effects add up (additive effect)