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We conducted a local filter on the local refined blocks maps by the local filtering option in cryoSPARC in order to maintain the low-frequency densities for model fitting

10.1038/s41392-020-0149-3 16 ChenX.KangR.KroemerG.TangD

13,14 Additionally, PI3K/Akt is involved in the apoptosis of PAECs, while AMPK and MAPK pathways contribute to metabolic adaptation and stress responses