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Avoid alcohol, excessive caffeine, smoking, and certain medications like high-dose paracetamol, chemotherapy drugs, and specific antibiotics

reported that 6 EBV + GC patients who received fluorouracil and platinum as first-line of chemotherapy had a 3-year survival rate of 80% compared to 26.5% in EBV GC patients (295)

In a few studies, the oral form has also effectively reduced dark spots and achieved skin lightening

18 patients (85.7%) improved with UDCA only within a median of 36 days (5-168)

In addition to the above, some natural medicines have been proved to have anti-RA activity ( Table 1 ): polyphenols including curcumin, chlorogenic acid and punicalagen, flavonoids including hesperidin, 7,3-dimethoxyhesperidin, kaempferol and genistein, terpenes including pentaacetyl geniposide, gentiopicrin and betulinic acid, glycosides including emodin, and cyanidin-3-O-glucuronide, alkaloids including berberine and matrine, -mangiferin (a xanthone derivative of mangosteen pericarp), cinnamaldehyde (an aldehyde active compound Chinese medicine herb Cinnamomum cassia), thymoquinone (the main component of the volatile oil in Nigella sativa L.), periplocin (one of the main active components in Periploca sepium Bunge)