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Whats more, the NOD-like receptor family pyrin domain-containing 3 (NLRP3), also upregulated by the activation of NF-B, 38 forms inflammasome and activates protein kinase C epsilon (PKC), 39 thus imparting IRS-1 40 (Fig

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in: PubMed | Google Scholar Published June 8, 2023 - More info Ischemic-reperfusion injury (IRI) is a major pathogenic factor in acute kidney injury (AKI), which directly leads to the hypoxic injury of renal tubular epithelial cells (RTECs)