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Activating an oncogenic pathway in cognitively concerned but otherwise healthy people requires a high evidence bar that hasnt been met

However, while vitamin B12 supplements may help those with neurological function concerns or deficiencies, the evidence isnt strong enough to support its use as a standalone treatment for depression

Ill be recommending them

Theres yet to be a firmly established causation between vitamin B-12 deficiency and depression, but there is growing evidence that low B-12 levels may contribute to depressive symptoms, especially in older adults or those with other risk factors

That's probably going to be a niche case condition that people would want to use that