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doi: 10.1038/s41388-021-01838-x 49 LiJYueHYuHLuXXueX

In Pappa knock-out animals a 20-30% reduction in body weight was reported (31)

None of the mechanisms summarized here have been independently verified in adequately powered human clinical trials of 5-Amino-1MQ specifically

Vitamin B12 deficiency and use of proton pump inhibitors: a systematic review and meta-analysis

With the mainstream availability of these substances you would expect athletes to be using them, but the positive statistics dont show that, at least not yet