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In the 2 largest cohorts, encompassing 61 of 64 patients, sirolimus use was reported as monotherapy without corticosteroids, providing a similar ORR of 88.7%

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We also used several global or near-global databases produced as compilations from old reports and scientific papers (L5), for example: ISRIC's WoSIS (Batjes et al., 2024), Fine Root Ecology Database (FRED) (Iversen et al., 2017), Soil Health DB (Jian et al., 2020), and the International Soil Carbon Network Database (Harden et al., 2018)