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Tisi A, Feligioni M, Passacantando M, Ciancaglini M, Maccarone R

Furthermore, reproducibility and quality control during hydrogel synthesis, sterilization, and clinical preparation are critical to meet regulatory standards

Briefly, template cDNA (1 l), SYBR green (2x) mixes (5 l), forward and reverse primers (0.5 l each) and total reaction volume up to 10 l was made using nuclease-free water

By enhancing ER protein-folding capacity, reducing the accumulation of misfolded proteins, and activating adaptive signaling programs, the UPR allows cancer cells to survive and proliferate in hostile microenvironments that would otherwise compromise cellular viability