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By scavenging excessive ROS, polysaccharides can prevent the activation of pro-tumorigenic pathways (e.g., NF-B and MAPK) that are driven by oxidative stress (136)

Exploration of the influence of different biomimetic designs of 3D printed multi-material artificial spinal disc on the natural mechanics restoration

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The VA formulary includes tirzepatide (as Zepbound) for weight management under specific clinical criteria

Interestingly, a retrospective cohort study highlighted that cigarette smoking appears to be negatively associated with DIH, which is surprising as induction of CYP2E1 in smokers is expected to increase exposure to toxic metabolites (Zaverucha-do-Valle et al., 2014)