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Bajaj JS, Sheikh MY, Chojkier M, Balart L, Sherker AH, Vemuru R, Sussman NL, Vierling J, Morelli G, Anderson KE, Harris MS, Mullen KD

Besides, our findings showed that the Tibetan-specific M9a haplogroup enhanced mitophagy but did not significantly reduce inflammation when compared with the M7/8 haplogroup

With regard to the substantial clinical improvement criterion, the applicant asserted that sabizabulin represents a substantial clinical improvement over existing technologies because sabizabulin has been shown to significantly improve clinical outcomes relative to other COVID-19 treatments because in a randomized, multicenter placebo-controlled phase 3 clinical trial, sabizabulin was associated with: reduction of least one clinically significant adverse event (SAE)

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Park J, Foox J, Hether T, Danko DC, Warren S, Kim Y, et al