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These are rare at the doses used in supervised clinical care and when they occur, they're typically mild and transient

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Other drug options include Amantadine to help with tremors, Catechol-O-methyl transferase (COMT) inhibitors to prevent COMT from deactivating levodopa, Anticholinergic drugs to reduce tremors by blocking the neurotransmitter acetylcholine, and Adenosine A2A receptor antagonists, which can work in a similar manner to levodopa to reduce symptoms during levodopa off times

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Dihexa has gained significant attention in laboratory studies involving learning pathways, synaptogenesis models, neuronal growth factor signaling, memory formation research, and neuroplasticity investigations