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Local viral delivery of the IGF-I isoforms promoted muscle hypertrophy in young mice, and the effect was isoform- and age-dependent: in growing animals both IGF-IA and IGF-IB enlarged muscle, whereas in older (six-month) animals only IGF-IA produced significant hypertrophy, suggesting the bioavailability or receptor affinity of the IGF-IB isoform diminishes with age

Elevated oxygen consumption, prolonged exposure to light, and excessive intake of PUFAs and photosensitizers may cause retinal ROS buildup and induce oxidative stress

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it inactivates microorganisms in foods due to permeabilization of cell membranes 394,473,474,475,476,477

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