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Janus-faced amyloids: protectors and perpetrators in Neuro-PASC Controversial and disappointing results from two phase 3 trials of the monoclonal antibody, aducanumab that targets the reduction of insoluble A [324327], implies that merely suppressing or inhibiting the formation of insoluble A may not fully address the complex, multi-faceted functions of amyloid aggregation that drive the progression of AD and other neurodegenerative disorders

Sun Q, Li J, Gao F

This article was funded by the Science and technology project of Suzhou (SYWD2025096)

Option 1: 2mL of bacteriostatic water (5mg/mL concentration) Adding 2mL creates the highest practical concentration at 5mg per milliliter

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