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Besides, placentas from GDM pregnancies exhibited elevated levels of the oxidized DNA product, 8-OHdG [28], and significantly heightened levels of lipid peroxidation (LPO) and 4-HNE [29, 30]

Additionally, other derivatives, including sulfonamide-modified gallic acid and Trolox-based compounds, exhibit enhanced antioxidant and anti-inflammatory properties, offering improved therapeutic potential [154]