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The guidelines are broken down into the following sections: Section I: ICD-10-CM Conventions, General Coding Guidelines, and Chapter-Specific Guidelines Section II: Selection of Principal Diagnosis Section III: Reporting Additional Diagnoses Section IV: Diagnostic Coding and Reporting Guidelines for Outpatient Services Section I, ICD-10-CM conventions were discussed in the diagnosis coding chapters

Hence, MTHFR deficiency results in hyperhomocysteinemia with clinical features similar to cystathionine -synthase deficiency

Haematological analysis (Appendix Table S3) revealed significantly lower red blood cell count, haemoglobin, haematocrit, and platelet count in the Clc 1:380 group compared with REF and GLI