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Timing patterns across both routes

These are highly potent compounds used at microgram-to-milligram level doses that escalate over weeks

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[538] Specifically, we proposed that the APP scoring policies at 414.1367(c)(1) for the calculation of the ACO's MIPS Quality performance category, 414.1367(c)(2) for the calculation of an ACO's MIPS Cost performance category, 414.1367(c)(3) for the calculation of an ACO's MIPS Improvement activities performance category, and 414.1367(c)(4) for the calculation of an ACO's MIPS Promoting Interoperability performance category would apply to ACOs that report the APP Plus quality measure set in performance year 2025 and subsequent performance years (89 FR 61859)

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