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Chronic low-grade inflammation has a documented role in promoting insulin resistance and other metabolic derangements in obesity and obesity-related conditions, including the metabolic syndrome, type 2 diabetes, cardiovascular disease and non-alcoholic steatohepatitis (Pavlov & Tracey, 2012)

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Whilst the true (not anecdotal or case reports) effects on melasma are lacking via large studies there are some reports that it can help with melasma pigmentation, especially in combination with procedures such as lasers & novel chemical peels