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408,409 While SANDO is most commonly associated with multiple mtDNA deletions due to POLG mutations, it can also be caused by mutations in the C10orf2 and RNASEH1 genes

It had been reported that there is an association between disruption of PI3K/AKT/CREB/BDNF pathway and the pathophysiology of neurological disorders, including ADHD (Alves et al

Lead author of the study, Anwar Mulugeta, PhD., said We found that people with higher levels of obesity, especially those with metabolically unfavorable and neutral adiposity subtypes, had much lower levels of gray brain matter, indicating that these people may have compromised brain function, which needed further investigation

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